Drugs & Vitamins

Indomethacin Injection Active Ingredients: Indomethacin Injection Representative Names: Indocin IV What is indomethacin injection? What should I tell my health care provider before I take this medicine? How should I use this medicine? What if I miss a dose? What drug(s) may interact with indomethacin? What side effects may I notice from receiving indomethacin? What should I watch for while taking indomethacin? Where can I keep my medicine? What is indomethacin injection? (Back to top) INDOMETHACIN (Indocin®) is a nonsteroidal anti-inflammatory drug (NSAID). Indomethacin injection treats a condition that some premature babies have called patent ductus arteriosus, in which a fetal blood vessel has not been closed before birth. Generic indomethacin injection is available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know about these conditions: •blood disorders •coronary artery bypass graft (CABG) surgery within the past 2 weeks •heart or circulation problems like angina, high blood pressure, heart failure, heart rhythm problems, history of heart attack, history of blood clots, or leg edema (fluid retention) •liver disease •seizures (convulsions) •history of stroke •an unusual or allergic reaction to indomethacin, aspirin, other salicylates, other NSAIDs, foods, dyes or preservatives •pregnant or trying to get pregnant •breast-feeding How should I use this medicine? (Back to top) Indomethacin is for injection into a vein. It is usually given as three intravenous doses at 12 to 24 hour intervals. What if I miss a dose? (Back to top) This does not apply. What drug(s) may interact with indomethacin? (Back to top) •alcohol •alendronate •aspirin and aspirin-like medicines •cidofovir •cyclosporine •entecavir •herbal products that contain feverfew, garlic, ginger, or ginkgo biloba •lithium •medicines for high blood pressure •medicines that affect platelets •medicines that treat or prevent blood clots such as warfarin and other 'blood thinners' •methotrexate •other antiinflammatory drugs (such as ibuprofen or prednisone) •pemetrexed •water pills (diuretics) Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving indomethacin? (Back to top) Some side effects noted in neonates include: •blood in urine •black, tarry stools •corneal deposits •diarrhea or constipation •difficulty breathing •fever, chills •reduced amount of urine passed •unusual bleeding or bruising •weight gain What should I watch for while taking indomethacin? (Back to top) You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how indomethacin affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Where can I keep my medicine? (Back to top) This does not apply. Last Updated:02/24/2006 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.